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Cellosaurus EDi001-A-3 (CVCL_LE53)

[Text version]

Cell line name EDi001-A-3
Synonyms AST22-1KO-1; AST23-1KO-1; AST22_SNCAKO Clone 1; AST23_SNCAKO Clone 1
Accession CVCL_LE53
Resource Identification Initiative To cite this cell line use: EDi001-A-3 (RRID:CVCL_LE53)
Comments From: University of Edinburgh; Edinburgh; United Kingdom.
Population: Caucasian.
Characteristics: The donor of the original cell line has 4 copies of SNCA. This edited cell line clone has 1 of the 4 alleles KO by CRISPR/Cas9.
Knockout cell: Method=CRISPR/Cas9 (1 of 4 alleles); HGNC; 11138; SNCA.
Derived from sampling site: Skin; dermis.
Disease Parkinson's disease (NCIt: C26845)
Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_AW97 (EDi001-A)
Sex of cell Female
Age at sampling 55Y
Category Induced pluripotent stem cell
Cell line collections EBiSC; EDi001-A-3
ECACC; 66540168
Cell line databases/resources hPSCreg; EDi001-A-3
Biological sample resources BioSamples; SAMEA3323899
Encyclopedic resources Wikidata; Q54831974
Entry history
Entry creation22-Aug-2017
Last entry update16-Dec-2021
Version number7