| Cell line name | EDi001-A-4 |
|---|---|
| Synonyms | AST22-2KO-6; AST23-2KO-6; AST22_SNCAKO Clone 6; AST23_SNCAKO Clone 6 |
| Accession | CVCL_LE54 |
| Resource Identification Initiative | To cite this cell line use: EDi001-A-4 (RRID:CVCL_LE54) |
| Comments | From: University of Edinburgh; Edinburgh; United Kingdom. Population: Caucasian. Characteristics: The donor of the original cell line has 4 copies of SNCA. This edited cell line clone has 2 of the 4 alleles KO by CRISPR/Cas9 (hPSCreg=EDi001-A-4). Knockout cell: Method=CRISPR/Cas9; HGNC; 11138; SNCA (Note=2 of 4 alleles). Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067. Cell type: Fibroblast of skin; CL=CL_0002620. |
| Disease | Parkinson disease 4, autosomal dominant (NCIt: C198604) Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_AW97 (EDi001-A) |
| Sex of cell | Female |
| Age at sampling | 55Y |
| Category | Induced pluripotent stem cell |
| Cross-references | |
| Cell line collections (Providers) | EBiSC; EDi001-A-4 - Discontinued
ECACC; 66540169 - Discontinued |
| Cell line databases/resources | hPSCreg; EDi001-A-4 |
| Biological sample resources | BioSamples; SAMEA3323960 |
| Encyclopedic resources | Wikidata; Q54831975 |
| Entry history | |
| Entry creation | 22-Aug-2017 |
| Last entry update | 30-Jan-2024 |
| Version number | 13 |