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Cellosaurus HuH-7T1 (CVCL_LG22)

[Text version]

Cell line name HuH-7T1
Accession CVCL_LG22
Resource Identification Initiative To cite this cell line use: HuH-7T1 (RRID:CVCL_LG22)
Comments Population: Japanese.
Characteristics: Compared to the parent Huh-7 cell line, permits improved HCV production when infected with strain JFH-1.
Sequence variations Homozygous for KDR p.Gln472His (c.1416A>T) (from parent cell line).
POLD3 p.Lys70Arg (c.209A>G) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Homozygous for TP53 p.Tyr220Cys (c.659A>G) (ClinVar=VCV000127819) (from parent cell line).
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0336 (Huh-7)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line

PubMed=23285155; DOI=10.1371/journal.pone.0052697
Murayama A., Sugiyama N., Yoshimura S., Ishihara-Sugano M., Masaki T., Kim S., Wakita T., Mishiro S., Kato T.
A subclone of HuH-7 with enhanced intracellular hepatitis C virus production and evasion of virus related-cell cycle arrest.
PLoS ONE 7:E52697-E52697(2012)

Other Wikidata; Q54896859
Entry history
Entry creation15-Nov-2017
Last entry update02-Jul-2020
Version number6