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Cellosaurus HT-29/B6 (CVCL_LJ30)

[Text version]

Cell line name HT-29/B6
Synonyms HT29/B6
Accession CVCL_LJ30
Resource Identification Initiative To cite this cell line use: HT-29/B6 (RRID:CVCL_LJ30)
Comments Characteristics: Derived from a glucose-free culture of HT-29.
Sequence variations Heterozygous for APC p.Glu853Ter (c.2557G>T) and p.Thr1556fs*3 (c.4666_4667insA) (from parent cell line).
Heterozygous for BRAF p.Val600Glu (c.1799T>A) (ClinVar=VCV000013961) (from parent cell line).
Heterozygous for PIK3CA p.Pro449Thr (c.1345C>A) (from parent cell line).
Homozygous for SMAD4 p.Gln311Ter (c.931C>T) (from parent cell line).
Homozygous for TP53 p.Arg273His (c.818G>A) (ClinVar=VCV000012366) (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0320 (HT-29)
Sex of cell Female
Age at sampling 44Y
Category Cancer cell line

PubMed=1656765; DOI=10.1152/ajpcell.1991.261.4.C574
Kreusel K.M., Fromm M., Schulzke J.-D., Hegel U.
Cl- secretion in epithelial monolayers of mucus-forming human colon cells (HT-29/B6).
Am. J. Physiol. 261:C574-C582(1991)

PubMed=11533143; DOI=10.1111/j.1469-7793.2001.00541.x
Bojarski C., Gitter A.H., Bendfeldt K., Mankertz J., Schmitz H., Wagner S., Fromm M., Schulzke J.-D.
Permeability of human HT-29/B6 colonic epithelium as a function of apoptosis.
J. Physiol. (Lond.) 535:541-552(2001)

Other Wikidata; Q54896526
Entry history
Entry creation15-Nov-2017
Last entry update02-Jul-2020
Version number7