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Cellosaurus HB1.F3 (CVCL_LJ44)

Cell line name HB1.F3
Synonyms F3; F3-WT
Accession CVCL_LJ44
Resource Identification Initiative To cite this cell line use: HB1.F3 (RRID:CVCL_LJ44)
Comments Transfected with: UniProtKB; P01110; Avian myelocytomatosis virus MC29 v-Myc.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transformant: v-Myc.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Fetal brain, telencephalon; UBERON=UBERON_0014371.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_B7F6 (F3-effLuc)CVCL_LJ45 (HB1.F3.CD21)CVCL_LJ46 (HB1.F3.EGFRviii)
CVCL_LJ47 (HB1.F3.Ngn1)CVCL_LJ48 (HB1.F3.Ras)
Sex of cell Female
Age at sampling 14FW
Category Transformed cell line
Publications

PubMed=12167771; DOI=10.1097/00001756-200208070-00020
Cho T., Bae J.-H., Choi H.B., Kim S.S., McLarnon J.G., Suh-Kim H., Kim S.U., Min C.K.
Human neural stem cells: electrophysiological properties of voltage-gated ion channels.
NeuroReport 13:1447-1452(2002)

PubMed=15484694; DOI=10.1111/j.1440-1789.2004.00552.x
Kim S.U.
Human neural stem cells genetically modified for brain repair in neurological disorders.
Neuropathology 24:159-171(2004)

PubMed=19813087; DOI=10.1007/s10571-009-9466-3
Satoh J.-i., Obayashi S., Tabunoki H., Wakana T., Kim S.U.
Stable expression of neurogenin 1 induces LGR5, a novel stem cell marker, in an immortalized human neural stem cell line HB1.F3.
Cell. Mol. Neurobiol. 30:415-426(2010)

PubMed=21755312; DOI=10.1007/s12015-011-9280-4
Lee J.-S., Lee H.J., Moon B.-H., Song S.-H., Lee M.-O., Shim S.H., Kim H.S., Lee M.C., Kwon J.T., Fornace A.J. Jr., Kim S.U., Cha H.J.
Generation of cancerous neural stem cells forming glial tumor by oncogenic stimulation.
Stem Cell Rev. Rep. 8:532-545(2012)

PubMed=25198726; DOI=10.1371/journal.pone.0105129
Hwang D.W., Jin Y., Lee D.H., Kim H.Y., Cho H.N., Chung H.J., Park Y., Youn H., Lee S.J., Lee H.J., Kim S.U., Wang K.-C., Lee D.S.
In vivo bioluminescence imaging for prolonged survival of transplanted human neural stem cells using 3D biocompatible scaffold in corticectomized rat model.
PLoS ONE 9:E105129-E105129(2014)

PubMed=25096191; DOI=10.1093/neuonc/nou145
Lee J.-S., Park J.-R., Kwon O.-S., Lee T.-H., Nakano I., Miyoshi H., Chun K.-H., Park M.-J., Lee H.J., Kim S.U., Cha H.-J.
SIRT1 is required for oncogenic transformation of neural stem cells and for the survival of 'cancer cells with neural stemness' in a p53-dependent manner.
Neuro-oncol. 17:95-106(2015)

PubMed=28830458; DOI=10.1186/s12943-017-0703-y
Kwon S.-J., Kwon O.-S., Kim K.-T., Go Y.-H., Yu S.-I., Lee B.-H., Miyoshi H., Oh E., Cho S.-J., Cha H.-J.
Role of MEK partner-1 in cancer stemness through MEK/ERK pathway in cancerous neural stem cells, expressing EGFRviii.
Mol. Cancer 16:140.1-140.13(2017)

Cross-references
Anatomy/cell type resources BTO; BTO:0002893
Encyclopedic resources Wikidata; Q54881352
Gene expression databases GEO; GSM456723
GEO; GSM456725
Entry history
Entry creation15-Nov-2017
Last entry update29-Jun-2023
Version number7