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Cellosaurus EJ-30 (CVCL_LN34)

[Text version]
Cell line name EJ-30
Synonyms EJ30
Accession CVCL_LN34
Resource Identification Initiative To cite this cell line use: EJ-30 (RRID:CVCL_LN34)
Comments Problematic cell line: Contaminated. Parent cell line (Ej138) has been shown to be a T24 derivative.
Population: Caucasian; Swedish.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; 5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2443 (Ej138)
Children:
CVCL_LN35 (EJ-30 clone A3)CVCL_LN36 (EJ-30 clone B3)CVCL_F666 (EJ-30tgr)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
Publications

PubMed=9419347; DOI=10.1073/pnas.95.1.167
Clarke D.J., Gimenez-Abian J.F., Tonnies H., Neitzel H., Sperling K., Downes C.S., Johnson R.T.
Creation of monosomic derivatives of human cultured cell lines.
Proc. Natl. Acad. Sci. U.S.A. 95:167-171(1998)

PubMed=10453083; DOI=10.2307/3580322
Forrester H.B., Yeh R.-F., Dewey W.C.
A dose response for radiation-induced intrachromosomal DNA rearrangements detected by inverse polymerase chain reaction.
Radiat. Res. 152:232-238(1999)

Cross-references
Cell line databases/resources cancercelllines; CVCL_LN34
Encyclopedic resources Wikidata; Q54832170
Entry history
Entry creation15-Nov-2017
Last entry update05-Oct-2023
Version number11