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Cellosaurus JMN-1B (CVCL_M006)

Cell line name JMN-1B
Synonyms JMN 1B; JMN1B
Accession CVCL_M006
Resource Identification Initiative To cite this cell line use: JMN-1B (RRID:CVCL_M006)
Comments Population: Caucasian.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gly245Ser (c.733G>A); ClinVar=VCV000012365; Zygosity=Homozygous (from parent cell line).
Disease Pleural biphasic mesothelioma (NCIt: C45665)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_M005 (JMN)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line
Publications

PubMed=2787682; DOI=10.1182/blood.V74.3.940.940
Demetri G.D., Zenzie B.W., Rheinwald J.G., Griffin J.D.
Expression of colony-stimulating factor genes by normal human mesothelial cells and human malignant mesothelioma cells lines in vitro.
Blood 74:940-946(1989)

PubMed=15920167; DOI=10.1016/S0002-9440(10)62492-3
Gordon G.J., Rockwell G.N., Jensen R.V., Rheinwald J.G., Glickman J.N., Aronson J.P., Pottorf B.J., Nitz M.D., Richards W.G., Sugarbaker D.J., Bueno R.
Identification of novel candidate oncogenes and tumor suppressors in malignant pleural mesothelioma using large-scale transcriptional profiling.
Am. J. Pathol. 166:1827-1840(2005)

PubMed=19853261; DOI=10.1016/j.jtcvs.2009.06.027
Hartman M.-L., Esposito J.M., Yeap B.Y., Sugarbaker D.J.
Combined treatment with cisplatin and sirolimus to enhance cell death in human mesothelioma.
J. Thorac. Cardiovasc. Surg. 139:1233-1240(2010)

Cross-references
Encyclopedic resources Wikidata; Q54899009
Gene expression databases GEO; GSM49617
Entry history
Entry creation06-May-2013
Last entry update29-Jun-2023
Version number10