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Cellosaurus MLO-Y4 (CVCL_M098)

[Text version]

Cell line name MLO-Y4
Synonyms MLOY4; Murine Long bone Osteocyte-Y4
Accession CVCL_M098
Resource Identification Initiative To cite this cell line use: MLO-Y4 (RRID:CVCL_M098)
Comments Group: Space-flown cell line (cellonaut).
Characteristics: Useful to study effects of fluid flow and substrate stretching on activation of osteocyte-specific signaling pathways (Kerafast).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: (C57BL/6J x BALB/cJ) F2.
Age at sampling 14D
Category Transformed cell line

PubMed=9421234; DOI=10.1359/jbmr.1997.12.12.2014
Kato Y., Windle J.J., Koop B.A., Mundy G.R., Bonewald L.F.
Establishment of an osteocyte-like cell line, MLO-Y4.
J. Bone Miner. Res. 12:2014-2023(1997)

PubMed=10084404; DOI=10.1007/s007740050066
Bonewald L.F.
Establishment and characterization of an osteocyte-like cell line, MLO-Y4.
J. Bone Miner. Metab. 17:61-65(1999)

PubMed=12412815; DOI=10.1359/jbmr.2002.17.11.2068
Zhao S., Zhang Y.K., Harris S., Ahuja S.S., Bonewald L.F.
MLO-Y4 osteocyte-like cells support osteoclast formation and activation.
J. Bone Miner. Res. 17:2068-2079(2002)

PubMed=22130923; DOI=10.1007/978-1-61779-415-5_6
Rosser J., Bonewald L.F.
Studying osteocyte function using the cell lines MLO-Y4 and MLO-A5.
Methods Mol. Biol. 816:67-81(2012)

Cell line collections Kerafast; EKC002
Cell line databases/resources Lonza; 166
Ontologies BTO; BTO:0005489
EFO; EFO_0005394
Gene expression databases GEO; GSM1520095
GEO; GSM1520096
GEO; GSM1520097
GEO; GSM1520098
GEO; GSM1520099
GEO; GSM1520100
GEO; GSM1520101
GEO; GSM1520102
GEO; GSM1520103
GEO; GSM1520104
GEO; GSM1520105
GEO; GSM1520106
Other Wikidata; Q54905979
Entry history
Entry creation06-May-2013
Last entry updated02-Jul-2020
Version number14