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Cellosaurus LNCaP C-33 (CVCL_M129)

[Text version]

Cell line name LNCaP C-33
Synonyms LNCaP-C33; C-33; C33
Accession CVCL_M129
Resource Identification Initiative To cite this cell line use: LNCaP C-33 (RRID:CVCL_M129)
Comments Omics: Transcriptome analysis.
Sequence variations Homozygous for AR p.Thr878Ala (c.2632A>G) (from parent cell line).
Heterozygous for MEN1 p.Tyr313Ter (c.939T>A) (from parent cell line).
Heterozygous for PIK3R1 p.Arg639Ter (c.1915C>T) (from parent cell line).
PTEN p.Lys6Argfs*4 (c.17_18delAA) (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Derived from metastatic site: Left supraclavicular lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0395 (LNCaP)
Children:
CVCL_M130 (LNCaP C-51)CVCL_M131 (LNCaP C-81)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
Publications

PubMed=11705865
Karan D., Schmied B.M., Dave B.J., Wittel U.A., Lin M.-F., Batra S.K.
Decreased androgen-responsive growth of human prostate cancer is associated with increased genetic alterations.
Clin. Cancer Res. 7:3472-3480(2001)

PubMed=11870800; DOI=10.1002/pros.10054
Igawa T., Lin F.-F., Lee M.-S., Karan D., Batra S.K., Lin M.-F.
Establishment and characterization of androgen-independent human prostate cancer LNCaP cell model.
Prostate 50:222-235(2002)

PubMed=17977648; DOI=10.1016/j.canlet.2007.09.018
Singh A.P., Bafna S., Chaudhary K., Venkatraman G., Smith L., Eudy J.D., Johansson S.L., Lin M.-F., Batra S.K.
Genome-wide expression profiling reveals transcriptomic variation and perturbed gene networks in androgen-dependent and androgen-independent prostate cancer cells.
Cancer Lett. 259:28-38(2008)

Cross-references
Other Wikidata; Q54902812
Entry history
Entry creation06-May-2013
Last entry update02-Jul-2020
Version number11