ID   LNCaP C-33
AC   CVCL_M129
SY   LNCaP-C33; C-33; C33
DR   cancercelllines; CVCL_M129
DR   Wikidata; Q54902812
RX   PubMed=11705865;
RX   PubMed=11870800;
RX   PubMed=17977648;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
DI   NCIt; C4863; Prostate carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0395 ! LNCaP
SX   Male
AG   50Y
CA   Cancer cell line
DT   Created: 06-05-13; Last updated: 05-10-23; Version: 17
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RX   PubMed=11705865;
RA   Karan D., Schmied B.M., Dave B.J., Wittel U.A., Lin M.-F., Batra S.K.;
RT   "Decreased androgen-responsive growth of human prostate cancer is
RT   associated with increased genetic alterations.";
RL   Clin. Cancer Res. 7:3472-3480(2001).
//
RX   PubMed=11870800; DOI=10.1002/pros.10054;
RA   Igawa T., Lin F.-F., Lee M.-S., Karan D., Batra S.K., Lin M.-F.;
RT   "Establishment and characterization of androgen-independent human
RT   prostate cancer LNCaP cell model.";
RL   Prostate 50:222-235(2002).
//
RX   PubMed=17977648; DOI=10.1016/j.canlet.2007.09.018;
RA   Singh A.P., Bafna S., Chaudhary K., Venkatraman G., Smith L.,
RA   Eudy J.D., Johansson S.L., Lin M.-F., Batra S.K.;
RT   "Genome-wide expression profiling reveals transcriptomic variation and
RT   perturbed gene networks in androgen-dependent and androgen-independent
RT   prostate cancer cells.";
RL   Cancer Lett. 259:28-38(2008).
//