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Cellosaurus BT-12 (CVCL_M155)

[Text version]

Cell line name BT-12
Synonyms BT12
Accession CVCL_M155
Resource Identification Initiative To cite this cell line use: BT-12 (RRID:CVCL_M155)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: NCI Pediatric Preclinical Testing Program (PPTP) cell line panel.
From: Biegel J.; Children's Hospital of Philadelphia; Philadelphia; USA.
Doubling time: 27 hours (PubMed=20922763).
Omics: Deep exome analysis.
Disease Atypical teratoid/rhabdoid tumor (NCIt: C6906)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 2M
Category Cancer cell line
STR profile Source(s): COG; PubMed=20922763

Markers:
AmelogeninX
CSF1PO10,12
D2S133823
D3S135815,16
D5S81812
D7S8209,12
D8S117913,15
D13S31711,13
D16S53911,12
D18S5113,14
D19S43312,14
D21S1129,33.2
FGA22
TH017,9
TPOX8,11
vWA16,18

Run an STR similarity search on this cell line
Web pages http://www.cogcell.org/dl/BrainTumorDataSheets/BT-12_Cell_Line_Data_Sheet_COGcell_org.pdf
http://www.cogcell.org/cellreqs-ncipptp.php
http://www.pptpinvitro.org/cell_lines_panel.php
Publications

PubMed=17446062; DOI=10.1016/j.ejca.2007.03.003
D'cunja J., Shalaby T., Rivera P., von Buren A., Patti R., Heppner F.L., Arcaro A., Rorke-Adams L.B., Phillips P.C., Grotzer M.A.
Antisense treatment of IGF-IR induces apoptosis and enhances chemosensitivity in central nervous system atypical teratoid/rhabdoid tumours cells.
Eur. J. Cancer 43:1581-1589(2007)

PubMed=20922763; DOI=10.1002/pbc.22801
Kang M.H., Smith M.A., Morton C.L., Keshelava N., Houghton P.J., Reynolds C.P.
National Cancer Institute pediatric preclinical testing program: model description for in vitro cytotoxicity testing.
Pediatr. Blood Cancer 56:239-249(2011)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line databases/resources CCLE; BT12_SOFT_TISSUE
Cell_Model_Passport; SIDM01514
DepMap; ACH-000160
Biological sample resources BioSample; SAMN10989598
Other Wikidata; Q54798448
Entry history
Entry creation06-May-2013
Last entry updated05-Jul-2019
Version number11