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Cellosaurus HepDE19 (CVCL_M178)

[Text version]

Cell line name HepDE19
Synonyms DE19
Accession CVCL_M178
Resource Identification Initiative To cite this cell line use: HepDE19 (RRID:CVCL_M178)
Comments Population: Caucasian.
Derived from sampling site: Liver.
Sequence variations Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line

PubMed=17804499; DOI=10.1128/JVI.01123-07
Guo H.-T., Jiang D., Zhou T.-L., Cuconati A., Block T.M., Guo J.-T.
Characterization of the intracellular deproteinized relaxed circular DNA of hepatitis B virus: an intermediate of covalently closed circular DNA formation.
J. Virol. 81:12472-12484(2007)

PubMed=17875990; DOI=10.1128/AAC.00541-07
Dougherty A.M., Guo H.-T., Westby G., Liu Y.-J., Simsek E., Guo J.-T., Mehta A., Norton P., Gu B.-H., Block T.M., Cuconati A.
A substituted tetrahydro-tetrazolo-pyrimidine is a specific and novel inhibitor of hepatitis B virus surface antigen secretion.
Antimicrob. Agents Chemother. 51:4427-4437(2007)

Other Wikidata; Q54882838
Entry history
Entry creation06-May-2013
Last entry update20-May-2021
Version number14