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Cellosaurus SK-Hep-1/CDDP (CVCL_M182)

Cell line name SK-Hep-1/CDDP
Synonyms SK-Hep1/DDP
Accession CVCL_M182
Resource Identification Initiative To cite this cell line use: SK-Hep-1/CDDP (RRID:CVCL_M182)
Comments Characteristics: Has lost chromosome Y.
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Caution: PubMed=20458768 describes SK-Hep-1/CDDP and does not cite PubMed=20109345 which describes SK-Hep1/DDP. As the two papers are from the same authors and that the described cell lines have identical characteristics it is probable that they are identical.
Sequence variations Heterozygous for BRAF p.Val600Glu (c.1799T>A) (from parent cell line).
Homozygous for CDKN2A deletion (from parent cell line).
Disease Hepatocellular carcinoma (NCIt: C3099)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0525 (SK-HEP-1)
Sex of cell Male
Age at sampling 52Y
Category Cancer cell line

Zhou Y., Ling X.-L.
Establishment of a cisplatin-induced multidrug resistance cell line SK-Hep1/DDP.
Chin. J. Cancer 29:167-171(2010)

PubMed=20458768; DOI=10.3748/wjg.v16.i18.2291
Zhou Y., Ling X.-L., Li S.-W., Li X.-Q., Yan B.
Establishment of a human hepatoma multidrug resistant cell line in vitro.
World J. Gastroenterol. 16:2291-2297(2010)

Other Wikidata; Q54953671