ID   HepG2/mdr1
AC   CVCL_M186
DR   Wikidata; Q54882860
RX   PubMed=17517188;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Transfected with: HGNC; 40; ABCB1.
CC   Derived from sampling site: Liver.
DI   NCIt; C3728; Hepatoblastoma
DI   ORDO; Orphanet_449; Hepatoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0027 ! Hep-G2
SX   Male
AG   15Y
CA   Cancer cell line
DT   Created: 06-05-13; Last updated: 20-05-21; Version: 13
//
RX   PubMed=17517188;
RA   Chen Y.-B., Yan M.-L., Gong J.-P., Xia R.-P., Liu L.-X., Li N.,
RA   Lu S.-C., Zhang J.-G., Zeng D.-B., Xie J.-G., Yang J.-Y., Yan L.-N.;
RT   "Establishment of hepatocellular carcinoma multidrug resistant
RT   monoclone cell line HepG2/mdr1.";
RL   Chin. Med. J. 120:703-707(2007).
//