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Cellosaurus HepG2/Adm (CVCL_M187)

[Text version]

Cell line name HepG2/Adm
Synonyms HepG2/ADM; Hep-G2/ADM; Hep G2/ADM
Accession CVCL_M187
Resource Identification Initiative To cite this cell line use: HepG2/Adm (RRID:CVCL_M187)
Comments Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
Sequence variations NRAS p.Gln61Leu (c.182A>T) (ClinVar=VCV000375874) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line

Zhai B.-J., Wu F., Shao Z.-Y., Hu K., Zhao C.L., Wang Z.-B.
Establishment of human hepatocellular carcinoma multidrug-resistance cell line (HepG2/Adm) and study apoptosis induced by low-frequency pulse ultrasound exposure.
Zhonghua Gan Zang Bing Za Zhi 12:95-98(2004)

Zhai B.-J., Wu F., Shao Z.-Y., Hu K., Wang Z.-B.
Establishment of human multidrug-resistant hepatocellular carcinoma cell line (HepG2/Adm) and biological characteristics evaluation.
Ai Zheng 23:391-395(2004)

PubMed=17075973; DOI=10.3748/wjg.v12.i41.6614
Zhai B.-J., Shao Z.-Y., Zhao C.-L., Hu K., Wu F.
Development and characterization of multidrug resistant human hepatocarcinoma cell line in nude mice.
World J. Gastroenterol. 12:6614-6619(2006)

Ontologies BTO; BTO:0006029
Other Wikidata; Q54882859
Entry history
Entry creation06-May-2013
Last entry update02-Jul-2020
Version number11