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Cellosaurus POLZ L2618M (CVCL_M250)

[Text version]

Cell line name POLZ L2618M
Synonyms Nalm-6-MSH+/TK+/-/REV3L L2618M
Accession CVCL_M250
Resource Identification Initiative To cite this cell line use: POLZ L2618M (RRID:CVCL_M250)
Comments Knockout cell: Method=Homologous recombination (1 of 2 alleles); HGNC; 11830; TK1.
Transfected with: HGNC; 7235; MSH2 (exons 9 to 16).
Derived from sampling site: Peripheral blood.
Sequence variations REV3L p.Leu2618Met; by homologous recombination.
Heterozygous for EGFR p.Arg1068Ter (c.3202C>T) (from parent cell line).
Heterozygous for NRAS p.Ala146Thr (c.436G>A) (from parent cell line).
Heterozygous for RARA p.Gln45Ter (c.133C>T) (from parent cell line).
Disease Adult B acute lymphoblastic leukemia (NCIt: C9143)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_UD71 (Nalm-6-MSH+/TK+/-)
Sex of cell Male
Age at sampling 19Y
Category Cancer cell line
STR profile Source(s): JCRB

Markers:
AmelogeninX,Y
CSF1PO14
D5S81811,13
D7S8208,12
D13S3179,13
D16S5399,11
TH018,9
TPOX8,10
vWA15,16

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Cross-references
Cell line collections JCRB; JCRB1490
Other Wikidata; Q54947740
Entry history
Entry creation05-Nov-2013
Last entry updated12-Mar-2020
Version number9