ID   KKU-M139
AC   CVCL_M259
SY   KKUM139; M139; KKU-139
DR   BTO; BTO:0005467
DR   Wikidata; Q54900005
RX   PubMed=16475706;
RX   PubMed=20493868;
RX   PubMed=21871105;
RX   PubMed=22926522;
RX   PubMed=25998688;
RX   PubMed=35640676;
CC   Population: Southeast Asian; Thai.
CC   Doubling time: 17.36 +- 1.26 hours (PubMed=25998688).
DI   NCIt; C35417; Intrahepatic cholangiocarcinoma
DI   NCIt; C27769; Opisthorchis viverrini-related cholangiocarcinoma
DI   ORDO; Orphanet_70567; Cholangiocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 21-03-23; Version: 12
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RX   PubMed=16475706;
RA   Panichakul T., Intachote P., Wongkajornsilp A., Sripa B., Sirisinha S.;
RT   "Triptolide sensitizes resistant cholangiocarcinoma cells to
RT   TRAIL-induced apoptosis.";
RL   Anticancer Res. 26:259-265(2006).
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RX   PubMed=20493868; DOI=10.1016/j.ijpara.2010.05.002;
RA   Yonglitthipagon P., Pairojkul C., Chamgramol Y., Mulvenna J.,
RA   Sripa B.;
RT   "Up-regulation of annexin A2 in cholangiocarcinoma caused by
RT   Opisthorchis viverrini and its implication as a prognostic marker.";
RL   Int. J. Parasitol. 40:1203-1212(2010).
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RX   PubMed=21871105; DOI=10.1186/1476-4598-10-102;
RA   Obchoei S., Weakley S.M., Wongkham S., Wongkham C., Sawanyawisuth K.,
RA   Yao Q.-Z., Chen C.-Y.;
RT   "Cyclophilin A enhances cell proliferation and tumor growth of liver
RT   fluke-associated cholangiocarcinoma.";
RL   Mol. Cancer 10:102.1-102.15(2011).
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RX   PubMed=22926522; DOI=10.1038/onc.2012.382;
RA   Kunkeaw N., Jeon S.H., Lee K., Johnson B.H., Tanasanvimon S.,
RA   Javle M., Pairojkul C., Chamgramol Y., Wongfieng W., Gong B.,
RA   Leelayuwat C., Lee Y.S.;
RT   "Cell death/proliferation roles for nc886, a non-coding RNA, in the
RT   protein kinase R pathway in cholangiocarcinoma.";
RL   Oncogene 32:3722-3731(2013).
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RX   PubMed=25998688; DOI=10.3892/ijo.2015.3019;
RA   Wattanawongdon W., Hahnvajanawong C., Namwat N., Kanchanawat S.,
RA   Boonmars T., Jearanaikoon P., Leelayuwat C., Techasen A., Seubwai W.;
RT   "Establishment and characterization of gemcitabine-resistant human
RT   cholangiocarcinoma cell lines with multidrug resistance and enhanced
RT   invasiveness.";
RL   Int. J. Oncol. 47:398-410(2015).
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RX   PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007;
RA   Isidan A., Yenigun A., Soma D., Aksu E., Lopez K., Park Y.,
RA   Cross-Najafi A., Li P., Kundu D., House M.G., Chakraborty S.,
RA   Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.;
RT   "Development and characterization of human primary cholangiocarcinoma
RT   cell lines.";
RL   Am. J. Pathol. 192:1200-1217(2022).
//