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Cellosaurus MCF-7/Taxol (CVCL_M355)

[Text version]

Cell line name MCF-7/Taxol
Accession CVCL_M355
Resource Identification Initiative To cite this cell line use: MCF-7/Taxol (RRID:CVCL_M355)
Comments Selected for resistance to: ChEBI; CHEBI:45863; Paclitaxel (Taxol).
Sequence variations Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (ClinVar=VCV000013655) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line

PubMed=20926015; DOI=10.1177/147323001003800424
Zuo K.-Q., Zhang X.-P., Zou J., Li D., Lv Z.-W.
Establishment of a paclitaxel resistant human breast cancer cell strain (MCF-7/Taxol) and intracellular paclitaxel binding protein analysis.
J. Int. Med. Res. 38:1428-1435(2010)

Other Wikidata; Q54904387
Entry history
Entry creation05-Nov-2013
Last entry update02-Jul-2020
Version number11