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Cellosaurus Hs578Ts(i)8 (CVCL_M363)

[Text version]

Cell line name Hs578Ts(i)8
Accession CVCL_M363
Resource Identification Initiative To cite this cell line use: Hs578Ts(i)8 (RRID:CVCL_M363)
Comments Characteristics: Invasive subclone of Hs 587T.
Doubling time: 22 hours (PubMed=18386134).
Derived from sampling site: Breast.
Sequence variations Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 5173; HRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012612; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Val157Phe (c.469G>T); ClinVar=VCV000012353; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0332 (Hs 578T)
Sex of cell Female
Age at sampling 74Y
Category Cancer cell line

PubMed=18386134; DOI=10.1007/s10585-008-9169-z
Hughes L., Malone C., Chumsri S., Burger A.M., McDonnell S.
Characterisation of breast cancer cell lines and establishment of a novel isogenic subclone to study migration, invasion and tumourigenicity.
Clin. Exp. Metastasis 25:549-557(2008)

Encyclopedic resources Wikidata; Q54896339
Entry history
Entry creation05-Nov-2013
Last entry update20-May-2021
Version number12