Home  |  Contact

Cellosaurus MCF-7/E6 (CVCL_M439)

[Text version]

Cell line name MCF-7/E6
Synonyms MCF7-E6; MCF 7 E6
Accession CVCL_M439
Resource Identification Initiative To cite this cell line use: MCF-7/E6 (RRID:CVCL_M439)
Comments Transfected with: UniProtKB; P03126; Human papillomavirus type 16 (HPV16) protein E6.
Sequence variations Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (ClinVar=VCV000013655) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=7712469
Fan S., Smith M.L., Rivet D.J. II, Duba D., Zhan Q., Kohn K.W., Fornace A.J. Jr., O'Connor P.M.
Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline.
Cancer Res. 55:1649-1654(1995)

Cross-references
Other Wikidata; Q54904362
Entry history
Entry creation05-Nov-2013
Last entry update02-Jul-2020
Version number13