Cellosaurus logo
expasy logo

Cellosaurus PCI-38 (CVCL_M471)

[Text version]
Cell line name PCI-38
Synonyms PCI38
Accession CVCL_M471
Resource Identification Initiative To cite this cell line use: PCI-38 (RRID:CVCL_M471)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Caucasian.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: CRISPR phenotypic screen.
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis by microarray.
Genome ancestry Source: PubMed=30894373

Origin% genome
African3.33
Native American0
East Asian, North3.92
East Asian, South0
South Asian6.82
European, North30.5
European, South55.42
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX,Y
CSF1PO12
D5S81811
D7S8209,10
D13S31712
D16S53913
TH016
TPOX8,11
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=8084624; DOI=10.1177/01945998941113P105
Snyderman C.H., Klapan I., Milanovich M., Heo D.S., Wagner R., Schwartz D.R., Johnson J.T., Whiteside T.L.
Comparison of in vivo and in vitro prostaglandin E2 production by squamous cell carcinoma of the head and neck.
Otolaryngol. Head Neck Surg. 111:189-196(1994)

PubMed=17312569; DOI=10.1002/hed.20478
Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y.
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=30971826; DOI=10.1038/s41586-019-1103-9
Behan F.M., Iorio F., Picco G., Goncalves E., Beaver C.M., Migliardi G., Santos R., Rao Y., Sassi F., Pinnelli M., Ansari R., Harper S., Jackson D.A., McRae R., Pooley R., Wilkinson P., van der Meer D.J., Dow D., Buser-Doepner C.A., Bertotti A., Trusolino L., Stronach E.A., Saez-Rodriguez J., Yusa K., Garnett M.J.
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
Nature 568:511-516(2019)

Cross-references
Cell line databases/resources Cell_Model_Passport; SIDM00155
Cosmic-CLP; 1240205
DepMap; ACH-002296
CRISP screens repositories BioGRID_ORCS_Cell_line; 988
Chemistry resources GDSC; 1240205
PharmacoDB; PCI38_1252_2019
Encyclopedic resources Wikidata; Q54938698
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1670343
Sequence databases EGA; EGAS00001000978
Entry history
Entry creation05-Nov-2013
Last entry update30-Jan-2024
Version number19