Cellosaurus UROtsa/F35 (CVCL_M721)

Cell line name UROtsa/F35
Accession CVCL_M721
Resource Identification Initiative To cite this cell line use: UROtsa/F35 (RRID:CVCL_M721)
Comments Problematic cell line: Contaminated. Shown to be a T24 derivative (PubMed=23691160).
Sequence variations Homozygous for HRAS p.Gly12Val (c.35G>T) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0554 (T24)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line

PubMed=16102566; DOI=10.1016/j.taap.2004.12.007
Drobna Z., Waters S.B., Devesa V., Harmon A.W., Thomas D.J., Styblo M.
Metabolism and toxicity of arsenic in human urothelial cells expressing rat arsenic (+3 oxidation state)-methyltransferase.
Toxicol. Appl. Pharmacol. 207:147-159(2005)

PubMed=23691160; DOI=10.1371/journal.pone.0064139
Johnen G., Rozynek P., von der Gathen Y., Bryk O., Zdrenka R., Johannes C., Weber D.G., Igwilo-Okuefuna O.B., Raiko I., Hippler J., Bruning T., Dopp E.
Cross-contamination of a UROtsa stock with T24 cells -- molecular comparison of different cell lines and stocks.
PLoS ONE 8:E64139-E64139(2013)

Other Wikidata; Q54991845