| Cell line name |
SUP-T1/Z29 |
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| Synonyms |
SUPT-1 / Z29 |
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| Accession |
CVCL_M772 |
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| Resource Identification Initiative |
To cite this cell line use: SUP-T1/Z29 (RRID:CVCL_M772) |
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| Comments |
Population: Caucasian.
Virology: Infected by human herpesvirus 6B (HHV-6B) strain Z29.
Caution: Was discontinued from the HIVReagentProgram because the cell line seemed to have also been infected by HIV-1 (personal communication of Rashid S.).
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Cell type: T-cell; CL=CL_0000084. |
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| Sequence variations |
- Mutation; HGNC; 3236; EGFR; Simple; p.Cys251Tyr (c.752G>A); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 6342; KIT; Simple; p.Arg177His (c.530G>A); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 7029; MET; Simple; p.Arg191Trp (c.571C>T); ClinVar=VCV000568557; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Asp (c.1635G>T); ClinVar=VCV000217293; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu970Lys (c.2908G>A); ClinVar=VCV001057635; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 9585; PTCH1; Simple; p.Arg682Cys (c.2044C>T); ClinVar=VCV000237466; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 15533; SPRY4; Simple; p.Arg25Trp (c.73C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Arg267Leu (c.800G>T); ClinVar=VCV000852206; Zygosity=Heterozygous (from parent cell line).
|
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| Disease |
Childhood T lymphoblastic lymphoma (NCIt: C7210)
T-cell non-Hodgkin lymphoma (ORDO: Orphanet_171918) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_1714 (SUP-T1) |
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| Sex of cell |
Male |
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| Age at sampling |
8Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=11689646; DOI=10.1128/JVI.75.23.11641-11650.2001
Mayne M., Cheadle C., Soldan S.S., Cermelli C., Yamano Y., Akhyani N., Nagel J.E., Taub D.D., Becker K.G., Jacobson S.
Gene expression profile of herpesvirus-infected T cells obtained using immunomicroarrays: induction of proinflammatory mechanisms.
J. Virol. 75:11641-11650(2001) |
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| Cross-references |
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| Cell line collections (Providers) |
HIVReagentProgram; ARP-12183 - Discontinued
|
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| Cell line databases/resources |
cancercelllines; CVCL_M772
|
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| Encyclopedic resources |
Wikidata; Q54970884
|
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| Entry history |
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| Entry creation | 05-Nov-2013 |
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| Last entry update | 05-Oct-2023 |
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| Version number | 16 |
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