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Cellosaurus DDLS8817 (CVCL_M814)

Cell line name DDLS8817
Accession CVCL_M814
Resource Identification Initiative To cite this cell line use: DDLS8817 (RRID:CVCL_M814)
Comments Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Disease Dedifferentiated liposarcoma (NCIt: C3704)
Dedifferentiated liposarcoma (ORDO: Orphanet_99970)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=20713527; DOI=10.1158/0008-5472.CAN-10-0745
Brill E.R., Gobble R.M., Angeles C.V., Lagos-Quintana M., Crago A., Laxa B.U., DeCarolis P.L., Zhang L., Antonescu C.R., Socci N.D., Taylor B.S., Sander C., Koff A., Singer S.
ZIC1 overexpression is oncogenic in liposarcoma.
Cancer Res. 70:6891-6901(2010)

PubMed=21138865; DOI=10.1158/1078-0432.CCR-09-2886
Morozov A., Downey R.J., Healey J., Moreira A.L., Lou E., Franceschino A., Dogan Y., Leung R., Edgar M., La Quaglia M.P., Maki R.G., Moore M.A.S.
Benign mesenchymal stromal cells in human sarcomas.
Clin. Cancer Res. 16:5630-5640(2010)

PubMed=21335544; DOI=10.1158/0008-5472.CAN-10-3588
Gobble R.M., Qin L.-X., Brill E.R., Angeles C.V., Ugras S., O'Connor R.B., Moraco N.H., DeCarolis P.L., Antonescu C.R., Singer S.
Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis.
Cancer Res. 71:2697-2705(2011)

PubMed=21693658; DOI=10.1158/0008-5472.CAN-11-0890
Ugras S., Brill E.R., Jacobsen A., Hafner M., Socci N.D., DeCarolis P.L., Khanin R., O'Connor R.B., Mihailovic A., Taylor B.S., Sheridan R., Gimble J.M., Viale A.J., Crago A., Antonescu C.R., Sander C., Tuschl T., Singer S.
Small RNA sequencing and functional characterization reveals MicroRNA-143 tumor suppressor activity in liposarcoma.
Cancer Res. 71:5659-5669(2011)

PubMed=22328974; DOI=10.1158/2159-8290.CD-11-0181
Taylor B.S., DeCarolis P.L., Angeles C.V., Brenet F., Schultz N., Antonescu C.R., Scandura J.M., Sander C., Viale A.J., Socci N.D., Singer S.
Frequent alterations and epigenetic silencing of differentiation pathway genes in structurally rearranged liposarcomas.
Cancer Discov. 1:587-597(2011)

PubMed=22170698; DOI=10.1002/gcc.21917
Wu Y.V., Okada T., DeCarolis P.L., Socci N.D., O'Connor R.B., Geha R.C., Somberg C.J., Antonescu C.R., Singer S.
Restoration of C/EBPalpha in dedifferentiated liposarcoma induces G2/M cell cycle arrest and apoptosis.
Genes Chromosomes Cancer 51:313-327(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_M814
Encyclopedic resources Wikidata; Q54830937
Gene expression databases GEO; GSM529097
GEO; GSM1228008
Polymorphism and mutation databases Progenetix; CVCL_M814
Entry history
Entry creation05-Nov-2013
Last entry update05-Oct-2023
Version number10