ID   BFTC-905-diffuse
AC   CVCL_M889
DR   cancercelllines; CVCL_M889
DR   Wikidata; Q54796205
RX   PubMed=18398596;
CC   Population: Chinese; Taiwan.
CC   Characteristics: Differs from the BFTC-905-compact cell line by growing in a less organized, 'diffuse' manner, which involves colonies of cells exhibiting apparently normal cell-to-cell adhesion as well as individual cells outside of them (PubMed=18398596).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; c.673-2A>T (IVS6-2A>T); ClinVar=VCV000635388; Zygosity=Homozygous; Note=Splice acceptor mutation (from parent cell line).
CC   Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
DI   NCIt; C4912; Bladder carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1083 ! BFTC-905
SX   Female
AG   51Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 05-10-23; Version: 15
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RX   PubMed=18398596; DOI=10.1007/s00120-008-1687-4;
RA   Hatina J., Huckenbeck W., Rieder H., Seifert H.-H., Schulz W.A.;
RT   "Bladder carcinoma cell lines as models of the pathobiology of bladder
RT   cancer. Review of the literature and establishment of a new
RT   progression series.";
RL   Urologe A 47:724-734(2008).
//