ID   T24T
AC   CVCL_M892
DR   cancercelllines; CVCL_M892
DR   Wikidata; Q54971468
RX   PubMed=10679914;
RX   PubMed=12460916;
RX   PubMed=15520187;
RX   PubMed=29732388;
CC   Population: Caucasian; Swedish.
CC   Sequence variation: Mutation; HGNC; 5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
DI   NCIt; C4912; Bladder carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0554 ! T24
SX   Female
AG   82Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 05-10-23; Version: 14
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RX   PubMed=10679914; DOI=10.1002/(SICI)1098-2264(200003)27:3<252::AID-GCC5>3.0.CO;2-9;
RA   Gildea J.J., Golden W.L., Harding M.A., Theodorescu D.;
RT   "Genetic and phenotypic changes associated with the acquisition of
RT   tumorigenicity in human bladder cancer.";
RL   Genes Chromosomes Cancer 27:252-263(2000).
//
RX   PubMed=12460916;
RA   Harding M.A., Arden K.C., Gildea J.W., Gildea J.J., Perlman E.J.,
RA   Viars C., Theodorescu D.;
RT   "Functional genomic comparison of lineage-related human bladder cancer
RT   cell lines with differing tumorigenic and metastatic potentials by
RT   spectral karyotyping, comparative genomic hybridization, and a novel
RT   method of positional expression profiling.";
RL   Cancer Res. 62:6981-6989(2002).
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RX   PubMed=15520187; DOI=10.1158/0008-5472.CAN-04-0826;
RA   Nicholson B.E., Frierson H.F. Jr., Conaway M.R., Seraj J.M.,
RA   Harding M.A., Hampton G.M., Theodorescu D.;
RT   "Profiling the evolution of human metastatic bladder cancer.";
RL   Cancer Res. 64:7813-7821(2004).
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RX   PubMed=29732388; DOI=10.3233/BLC-180167;
RA   Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.;
RT   "Systematic review: characteristics and preclinical uses of bladder
RT   cancer cell lines.";
RL   Bladder Cancer 4:169-183(2018).
//