Cell line name |
T24T FL1 |
Synonyms |
FL1 |
Accession |
CVCL_M895 |
Resource Identification Initiative |
To cite this cell line use: T24T FL1 (RRID:CVCL_M895) |
Comments |
Population: Caucasian; Swedish. Characteristics: Produced by passage of the parent cell line through nude mice. Omics: Transcriptome analysis by microarray. Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255. |
Sequence variations |
- Mutation; HGNC; 5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
|
Disease |
Bladder carcinoma (NCIt: C4912) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_M892 (T24T) Children:
|
Sex of cell |
Female |
Age at sampling |
82Y |
Category |
Cancer cell line |
Publications | PubMed=15520187; DOI=10.1158/0008-5472.CAN-04-0826 Nicholson B.E., Frierson H.F. Jr., Conaway M.R., Seraj J.M., Harding M.A., Hampton G.M., Theodorescu D. Profiling the evolution of human metastatic bladder cancer. Cancer Res. 64:7813-7821(2004) PubMed=19147813; DOI=10.2353/ajpath.2009.080538 Smith S.C., Nicholson B., Nitz M.D., Frierson H.F. Jr., Smolkin M., Hampton G.M., El-Rifai W., Theodorescu D. Profiling bladder cancer organ site-specific metastasis identifies LAMC2 as a novel biomarker of hematogenous dissemination. Am. J. Pathol. 174:371-379(2009) PubMed=29732388; DOI=10.3233/BLC-180167 Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D. Systematic review: characteristics and preclinical uses of bladder cancer cell lines. Bladder Cancer 4:169-183(2018) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_M895
|
Encyclopedic resources |
Wikidata; Q54971470
|
Entry history |
Entry creation | 05-Nov-2013 |
Last entry update | 05-Oct-2023 |
Version number | 14 |
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