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Cellosaurus AT3LA LCL (CVCL_M910)

[Text version]
Cell line name AT3LA LCL
Synonyms Ataxia Telangiectasia 3 Los Angeles LCL; GM11261
Accession CVCL_M910
Resource Identification Initiative To cite this cell line use: AT3LA LCL (RRID:CVCL_M910)
Comments Population: African American.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Disease Ataxia telangiectasia syndrome (NCIt: C2887)
Ataxia telangiectasia (ORDO: Orphanet_100)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_B5ME ! AT3LA
Sex of cell Female
Age at sampling 16Y
Category Transformed cell line
Publications

PubMed=8808599
Wright J., Teraoka S., Onengut S., Tolun A., Gatti R.A., Ochs H.D., Concannon P.
A high frequency of distinct ATM gene mutations in ataxia-telangiectasia.
Am. J. Hum. Genet. 59:839-846(1996)

PubMed=9150358; DOI=10.1038/sj.onc.1201037
Watters D., Khanna K.K., Beamish H.J., Birrell G., Spring K., Kedar P., Gatei M., Stenzel D., Hobson K., Kozlov S., Zhang N., Farrell A., Ramsay J., Gatti R.A., Lavin M.F.
Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms.
Oncogene 14:1911-1921(1997)

PubMed=9168117; DOI=10.1038/387520a0
Shafman T., Khanna K.K., Kedar P., Spring K., Kozlov S., Yen T.J., Hobson K., Gatei M., Zhang N., Watters D., Egerton M., Shiloh Y., Kharbanda S., Kufe D.W., Lavin M.F.
Interaction between ATM protein and c-Abl in response to DNA damage.
Nature 387:520-523(1997)

PubMed=16166284; DOI=10.1158/0008-5472.CAN-04-1198
Araten D.J., Golde D.W., Zhang R.H., Thaler H.T., Gargiulo L., Notaro R., Luzzatto L.
A quantitative measurement of the human somatic mutation rate.
Cancer Res. 65:8111-8117(2005)

Cross-references
Cell line collections (Providers) Coriell; GM11261
Cell line databases/resources CLO; CLO_0025973
Biological sample resources BioSample; SAMN00800515
Encyclopedic resources Wikidata; Q54844945
Entry history
Entry creation05-Nov-2013
Last entry update29-Jun-2023
Version number17