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Cellosaurus NCE-G 59 (CVCL_N729)

[Text version]
Cell line name NCE-G 59
Synonyms NCE-G59; G-59; G59; NeuroChirurgie Eppendorf-Glioma 59
Accession CVCL_N729
Resource Identification Initiative To cite this cell line use: NCE-G 59 (RRID:CVCL_N729)
Comments Omics: SNP array analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Brain, left temporo-medial region.
Sequence variations
  • Gene deletion; HGNC; 8598; PANK1; Zygosity=Homozygous (PubMed=36139163).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Unspecified (PubMed=8253536).
HLA typing Source: PubMed=26589293
Class I
HLA-AA*25:01,68:01
HLA-BB*15:01,44:02
HLA-CC*03:03,05:01
Disease Anaplastic astrocytoma (NCIt: C9477)
Anaplastic astrocytoma (ORDO: Orphanet_251589)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 66Y
Category Cancer cell line
STR profile Source(s): PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO11,12
D3S135814,15
D5S81811,12
D7S82011,12
D8S117912
D13S31711,12
D16S53910,13
D18S5114,16
D21S1129,30.2
FGA21,24
Penta D10
Penta E13
TH016,9.3
TPOX8
vWA14,15

Run an STR similarity search on this cell line
Publications

PubMed=8253536; DOI=10.1002/ijc.2910550618
Anker L., Ohgaki H., Ludeke B.I., Herrmann H.-D., Kleihues P., Westphal M.
p53 protein accumulation and gene mutations in human glioma cell lines.
Int. J. Cancer 55:982-987(1993)

PubMed=8289093; DOI=10.1007/BF01324703
Hamel W., Westphal M., Shepard H.M.
Loss in expression of the retinoblastoma gene product in human gliomas is associated with advanced disease.
J. Neurooncol. 16:159-165(1993)

PubMed=8154317; DOI=10.1007/BF01476489
Westphal M., Hansel M., Hamel W., Kunzmann R., Holzel F.
Karyotype analyses of 20 human glioma cell lines.
Acta Neurochir. (Wien) 126:17-26(1994)

PubMed=16696057; DOI=10.1136/mp.49.2.M91
Xin L.W., Martinerie C., Zumkeller W., Westphal M., Perbal B.
Differential expression of novH and CTGF in human glioma cell lines.
Clin. Mol. Pathol. 49:M91-M97(1996)

DOI=10.1007/0-306-46861-1_11
Ali-Osman F.
Brain tumors.
(In) Human cell culture. Vol. 2. Cancer Cell Lines part 2; Masters J.R.W., Palsson B.O. (eds.); pp.167-184; Kluwer Academic Publishers; New York (1999)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25877200; DOI=10.1038/nature14397
Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=36139163; DOI=10.3390/biom12091323
Khadka S., Vien L., Leonard P., Bover L., Muller F.
Generation and validation of an anti-human PANK3 mouse monoclonal antibody.
Biomolecules 12:1323.1-1323.13(2022)

Cross-references
Cell line databases/resources cancercelllines; CVCL_N729
Biological sample resources BioSample; SAMN03471229
Chemistry resources PharmacoDB; G59_391_2019
Encyclopedic resources Wikidata; Q54907681
Experimental variables resources EFO; EFO_0006409
Gene expression databases ArrayExpress; E-MTAB-2706
Polymorphism and mutation databases IARC_TP53; 2148
Sequence databases EGA; EGAS00001000610
Entry history
Entry creation05-Nov-2013
Last entry update05-Oct-2023
Version number22