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Cellosaurus HaCaT YAP-5SA (CVCL_QX10)

[Text version]

Cell line name HaCaT YAP-5SA
Synonyms YAP_5SA_HaCAT
Accession CVCL_QX10
Resource Identification Initiative To cite this cell line use: HaCaT YAP-5SA (RRID:CVCL_QX10)
Comments Transfected with: HGNC; 16262; YAP1 (with p.Ser61Ala, p.Ser109Ala, p.Ser127Ala, p.Ser164Ala and p.Ser381Ala = YAP-5SA).
Omics: Deep RNAseq analysis.
Derived from sampling site: Back; skin; epidermis; keratinocyte.
Sequence variations Heterozygous for TP53 p.His179Tyr (c.535C>T) (ClinVar=VCV000127815) (from parent cell line).
Heterozygous for TP53 p.Arg282Trp (c.843_844CC>TT) (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0038 (HaCaT)
Sex of cell Male
Age at sampling 62Y
Category Spontaneously immortalized cell line

PubMed=26989177; DOI=10.1242/dev.133728
Elbediwy A., Vincent-Mistiaen Z.I., Spencer-Dene B., Stone R.K., Boeing S., Wculek S.K., Cordero J., Tan E.H., Ridgway R., Brunton V.G., Sahai E., Gerhardt H., Behrens A., Malanchi I., Sansom O.J., Thompson B.J.
Integrin signalling regulates YAP and TAZ to control skin homeostasis.
Development 143:1674-1687(2016)

Gene expression databases GEO; GSM2112564
GEO; GSM2112565
GEO; GSM2112566
Other Wikidata; Q54872315
Entry history
Entry creation15-Nov-2017
Last entry update12-Jan-2021
Version number7