Cellosaurus

Cellosaurus HaCaT YAP-5SA (CVCL_QX10)

Cross-references
Cell line name	HaCaT YAP-5SA
Synonyms	YAP_5SA_HaCAT
Accession	CVCL_QX10
Resource Identification Initiative	To cite this cell line use: HaCaT YAP-5SA (RRID:CVCL_QX10)
Comments	Transfected with: HGNC; 16262; YAP1 (with p.Ser61Ala, p.Ser109Ala, p.Ser127Ala, p.Ser164Ala and p.Ser381Ala = YAP-5SA). Omics: Deep RNAseq analysis. Derived from sampling site: Back; skin; epidermis; keratinocyte.
Sequence variations	Heterozygous for TP53 p.His179Tyr (c.535C>T) (ClinVar=VCV000127815) and p.Arg282Trp (c.843_844CC>TT) (from parent cell line).
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0038 (HaCaT)
Sex of cell	Male
Age at sampling	62Y
Category	Spontaneously immortalized cell line
Publications	PubMed=26989177; DOI=10.1242/dev.133728 Elbediwy A., Vincent-Mistiaen Z.I., Spencer-Dene B., Stone R.K., Boeing S., Wculek S.K., Cordero J., Tan E.H., Ridgway R., Brunton V.G., Sahai E., Gerhardt H., Behrens A., Malanchi I., Sansom O.J., Thompson B.J. Integrin signalling regulates YAP and TAZ to control skin homeostasis. Development 143:1674-1687(2016)
Gene expression databases	GEO; GSM2112564 GEO; GSM2112565 GEO; GSM2112566
Other	Wikidata; Q54872315
Entry history
Entry creation	15-Nov-2017
Last entry update	02-Jul-2020
Version number	6

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