ID   HaCaT YAP-5SA
AC   CVCL_QX10
SY   YAP_5SA_HaCAT
DR   GEO; GSM2112564
DR   GEO; GSM2112565
DR   GEO; GSM2112566
DR   Wikidata; Q54872315
RX   PubMed=26989177;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.His179Tyr (c.535C>T); ClinVar=VCV000127815; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg282Trp (c.843_844CC>TT); Zygosity=Heterozygous (from parent cell line).
CC   Transfected with: HGNC; 16262; YAP1 (with p.Ser61Ala, p.Ser109Ala, p.Ser127Ala, p.Ser164Ala and p.Ser381Ala = YAP-5SA).
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Back, skin, epidermis; UBERON=UBERON_0001068+UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0038 ! HaCaT
SX   Male
AG   62Y
CA   Spontaneously immortalized cell line
DT   Created: 15-11-17; Last updated: 29-06-23; Version: 11
//
RX   PubMed=26989177; DOI=10.1242/dev.133728;
RA   Elbediwy A., Vincent-Mistiaen Z.I., Spencer-Dene B., Stone R.K.,
RA   Boeing S., Wculek S.K., Cordero J., Tan E.H., Ridgway R.,
RA   Brunton V.G., Sahai E., Gerhardt H., Behrens A., Malanchi I.,
RA   Sansom O.J., Thompson B.J.;
RT   "Integrin signalling regulates YAP and TAZ to control skin
RT   homeostasis.";
RL   Development 143:1674-1687(2016).
//