Cellosaurus A431 siYAP (CVCL_QX11)

Cell line name A431 siYAP
Synonyms siYAP_A431
Accession CVCL_QX11
Resource Identification Initiative To cite this cell line use: A431 siYAP (RRID:CVCL_QX11)
Comments Knockout cell: Method=siRNA knockdown; HGNC; 16262; YAP1.
Sequence variation: TP53 p.Arg273His (from parent cell line).
Omics: Deep RNAseq analysis.
Disease Vulvar squamous cell carcinoma (NCIt: C4052)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0037 (A-431)
Sex of cell Female
Age at sampling 85Y
Category Cancer cell line

PubMed=26989177; DOI=10.1242/dev.133728
Elbediwy A., Vincent-Mistiaen Z.I., Spencer-Dene B., Stone R.K., Boeing S., Wculek S.K., Cordero J., Tan E.H., Ridgway R., Brunton V.G., Sahai E., Gerhardt H., Behrens A., Malanchi I., Sansom O.J., Thompson B.J.
Integrin signalling regulates YAP and TAZ to control skin homeostasis.
Development 143:1674-1687(2016)

Gene expression databases GEO; GSM2112552
GEO; GSM2112553
GEO; GSM2112554