ID   A431 siYAP
AC   CVCL_QX11
SY   siYAP_A431
DR   cancercelllines; CVCL_QX11
DR   GEO; GSM2112552
DR   GEO; GSM2112553
DR   GEO; GSM2112554
DR   Wikidata; Q54606911
RX   PubMed=26989177;
CC   Population: Caucasian.
CC   Knockout cell: Method=siRNA knockdown; HGNC; 16262; YAP1.
CC   Sequence variation: Gene fusion; HGNC; 3236; EGFR + HGNC; 9237; PPARGC1A; Name(s)=EGFR-PPARGC1A (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
DI   NCIt; C4819; Skin squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0037 ! A-431
SX   Female
AG   85Y
CA   Cancer cell line
DT   Created: 15-11-17; Last updated: 05-10-23; Version: 12
//
RX   PubMed=26989177; DOI=10.1242/dev.133728;
RA   Elbediwy A., Vincent-Mistiaen Z.I., Spencer-Dene B., Stone R.K.,
RA   Boeing S., Wculek S.K., Cordero J., Tan E.H., Ridgway R.,
RA   Brunton V.G., Sahai E., Gerhardt H., Behrens A., Malanchi I.,
RA   Sansom O.J., Thompson B.J.;
RT   "Integrin signalling regulates YAP and TAZ to control skin
RT   homeostasis.";
RL   Development 143:1674-1687(2016).
//