ID   A431 YAP-5SA
AC   CVCL_QX12
SY   YAP_5SA_A431
DR   cancercelllines; CVCL_QX12
DR   GEO; GSM2112556
DR   GEO; GSM2112557
DR   GEO; GSM2112558
DR   Wikidata; Q54606913
RX   PubMed=26989177;
CC   Population: Caucasian.
CC   Sequence variation: Gene fusion; HGNC; 3236; EGFR + HGNC; 9237; PPARGC1A; Name(s)=EGFR-PPARGC1A (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
CC   Transfected with: HGNC; 16262; YAP1 (with p.Ser61Ala, p.Ser109Ala, p.Ser127Ala, p.Ser164Ala and p.Ser381Ala = YAP-5SA).
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
DI   NCIt; C4819; Skin squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0037 ! A-431
SX   Female
AG   85Y
CA   Cancer cell line
DT   Created: 15-11-17; Last updated: 05-10-23; Version: 13
//
RX   PubMed=26989177; DOI=10.1242/dev.133728;
RA   Elbediwy A., Vincent-Mistiaen Z.I., Spencer-Dene B., Stone R.K.,
RA   Boeing S., Wculek S.K., Cordero J., Tan E.H., Ridgway R.,
RA   Brunton V.G., Sahai E., Gerhardt H., Behrens A., Malanchi I.,
RA   Sansom O.J., Thompson B.J.;
RT   "Integrin signalling regulates YAP and TAZ to control skin
RT   homeostasis.";
RL   Development 143:1674-1687(2016).
//