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Cellosaurus RDLD-1 (CVCL_QZ54)

[Text version]
Cell line name RDLD-1
Accession CVCL_QZ54
Resource Identification Initiative To cite this cell line use: RDLD-1 (RRID:CVCL_QZ54)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:175901; Gemcitabine (Gemzar).
Sequence variations
  • Mutation; HGNC; 2704; DCK; Simple; p.Trp92Ter (c.276G>A); Zygosity=Unspecified (PubMed=22490663).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0248 (DLD-1)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=22490663; DOI=10.1016/j.bbrc.2012.03.122
Saiki Y., Yoshino Y., Fujimura H., Manabe T., Kudo Y., Shimada M., Mano N., Nakano T., Lee Y., Shimizu S., Oba S., Fujiwara S., Shimizu H., Chen N., Nezhad Z.K., Jin G., Fukushige S., Sunamura M., Ishida M., Motoi F., Egawa S., Unno M., Horii A.
DCK is frequently inactivated in acquired gemcitabine-resistant human cancer cells.
Biochem. Biophys. Res. Commun. 421:98-104(2012)

Cross-references
Encyclopedic resources Wikidata; Q54949561
Entry history
Entry creation05-Mar-2018
Last entry update05-Oct-2023
Version number6