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Cellosaurus RMKN-28 (CVCL_QZ55)

Cell line name RMKN-28
Accession CVCL_QZ55
Resource Identification Initiative To cite this cell line use: RMKN-28 (RRID:CVCL_QZ55)
Comments Problematic cell line: Contaminated. Parent cell line (MKN28) has been shown to be a MKN74 derivative.
Selected for resistance to: ChEBI; CHEBI:175901; Gemcitabine (Gemzar).
Sequence variations TP53 p.Ile251Leu (c.751A>C) (PubMed=22490663).
Disease Gastric tubular adenocarcinoma (NCIt: C5473)
Derived from metastatic site: Liver.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1416 (MKN28)
Sex of cell Male
Age at sampling 37Y
Category Cancer cell line

PubMed=22490663; DOI=10.1016/j.bbrc.2012.03.122
Saiki Y., Yoshino Y., Fujimura H., Manabe T., Kudo Y., Shimada M., Mano N., Nakano T., Lee Y., Shimizu S., Oba S., Fujiwara S., Shimizu H., Chen N., Nezhad Z.K., Jin G., Fukushige S., Sunamura M., Ishida M., Motoi F., Egawa S., Unno M., Horii A.
DCK is frequently inactivated in acquired gemcitabine-resistant human cancer cells.
Biochem. Biophys. Res. Commun. 421:98-104(2012)

Other Wikidata; Q54950673