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Cellosaurus MCF-7-BAG (CVCL_R954)

[Text version]
Cell line name MCF-7-BAG
Synonyms MCF-7 BAG
Accession CVCL_R954
Resource Identification Initiative To cite this cell line use: MCF-7-BAG (RRID:CVCL_R954)
Comments Population: Caucasian.
Transfected with: UniProtKB; P00722; Escherichia coli lacZ.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=1384607; DOI=10.1016/0959-8049(92)90245-W
Brunner N., Thompson E.W., Spang-Thomsen M., Rygaard J., Dano K., Zwiebel J.A.
lacZ transduced human breast cancer xenografts as an in vivo model for the study of invasion and metastasis.
Eur. J. Cancer 28:1989-1995(1992)

Cross-references
Cell line databases/resources cancercelllines; CVCL_R954
Encyclopedic resources Wikidata; Q54904330
Entry history
Entry creation05-Nov-2013
Last entry update05-Oct-2023
Version number18