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Cellosaurus MDA-MB-231-BAG (CVCL_R956)

[Text version]

Cell line name MDA-MB-231-BAG
Synonyms MDA-MB-231 BAG
Accession CVCL_R956
Resource Identification Initiative To cite this cell line use: MDA-MB-231-BAG (RRID:CVCL_R956)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Transfected with: UniProtKB; P00722; E.coli lacZ.
Sequence variations Heterozygous for BRAF p.Gly464Val (c.1391G>T) (ClinVar=VCV000040364) (from parent cell line).
Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for KRAS p.Gly13Asp (c.38G>A) (ClinVar=VCV000012580) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Homozygous for TP53 p.Arg280Lys (c.839G>A) (ClinVar=VCV000376657) (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0062 (MDA-MB-231)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line

PubMed=1384607; DOI=10.1016/0959-8049(92)90245-W
Brunner N., Thompson E.W., Spang-Thomsen M., Rygaard J., Dano K., Zwiebel J.A.
lacZ transduced human breast cancer xenografts as an in vivo model for the study of invasion and metastasis.
Eur. J. Cancer 28:1989-1995(1992)

Ontologies BTO; BTO:0004474
Other Wikidata; Q54904596
Entry history
Entry creation05-Nov-2013
Last entry update02-Jul-2020
Version number13