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Cellosaurus HCC1937 shPARG (CVCL_RA87)

Cell line name HCC1937 shPARG
Synonyms shPARG HCC1937
Accession CVCL_RA87
Resource Identification Initiative To cite this cell line use: HCC1937 shPARG (RRID:CVCL_RA87)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Knockout cell: Method=shRNA knockdown; HGNC; 8605; PARG.
Omics: Poly-ADP-ribosylation by proteomics.
Sequence variations Homozygous for BRCA1 p.Gln1756Profs*74 (c.5266dupC) (from parent cell line).
Homozygous for TP53 p.Arg306Ter (c.916C>T) (from parent cell line).
Disease Ductal breast carcinoma (NCIt: C4017)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0290 (HCC1937)
Sex of cell Female
Age at sampling 24Y
Category Cancer cell line
Publications

PubMed=29166620; DOI=10.1016/j.celrep.2017.10.106
Zhen Y.-L., Zhang Y.-J., Yu Y.-H.
A cell-line-specific atlas of PARP-mediated protein Asp/Glu-ADP-ribosylation in breast cancer.
Cell Rep. 21:2326-2337(2017)

Cross-references
Other Wikidata; Q54881613