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Cellosaurus MCF-7 shPARG (CVCL_RA89)

[Text version]

Cell line name MCF-7 shPARG
Synonyms shPARG MCF7
Accession CVCL_RA89
Resource Identification Initiative To cite this cell line use: MCF-7 shPARG (RRID:CVCL_RA89)
Comments Knockout cell: Method=shRNA knockdown; HGNC; 8605; PARG.
Omics: Poly-ADP-ribosylation by proteomics.
Sequence variations Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (ClinVar=VCV000013655) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=29166620; DOI=10.1016/j.celrep.2017.10.106
Zhen Y.-L., Zhang Y.-J., Yu Y.-H.
A cell-line-specific atlas of PARP-mediated protein Asp/Glu-ADP-ribosylation in breast cancer.
Cell Rep. 21:2326-2337(2017)

Cross-references
Other Wikidata; Q54904325
Entry history
Entry creation05-Mar-2018
Last entry update02-Jul-2020
Version number4