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Cellosaurus SK-BR-3 shPARG (CVCL_RA92)

[Text version]
Cell line name SK-BR-3 shPARG
Synonyms shPARG SK-BR-3
Accession CVCL_RA92
Resource Identification Initiative To cite this cell line use: SK-BR-3 shPARG (RRID:CVCL_RA92)
Comments Population: Caucasian.
Knockout cell: Method=shRNA knockdown; HGNC; 8605; PARG.
Omics: Poly-ADP-ribosylation by proteomics.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; 1748; CDH1; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0033 (SK-BR-3)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line
Publications

PubMed=29166620; DOI=10.1016/j.celrep.2017.10.106
Zhen Y.-L., Zhang Y.-J., Yu Y.-H.
A cell-line-specific atlas of PARP-mediated protein Asp/Glu-ADP-ribosylation in breast cancer.
Cell Rep. 21:2326-2337(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_RA92
Encyclopedic resources Wikidata; Q54953619
Entry history
Entry creation05-Mar-2018
Last entry update05-Oct-2023
Version number9