ID   STBCi026-A
SY   SFC840-03-03; AH017-13; AH017, iPSc clone 13; iPS AH017-13; CTL2.1; Ctrl3#2
DR   BioSamples; SAMEA104493660
DR   EBiSC; STBCi026-A
DR   ECACC; 66540694
DR   GEO; GSM1831382
DR   GEO; GSM1831590
DR   hPSCreg; STBCi026-A
DR   Wikidata; Q54956408
RX   PubMed=26905200;
RX   PubMed=28591653;
RX   PubMed=28827786;
RX   PubMed=32359446;
CC   From: StemBANCC; UK.
CC   Omics: Transcriptome analysis.
CC   Derived from sampling site: Skin; dermis.
OX   NCBI_TaxID=9606; ! Homo sapiens
OI   CVCL_RB86 ! STBCi026-B
OI   CVCL_RB87 ! STBCi026-C
OI   CVCL_RB88 ! STBCi026-D
SX   Female
AG   67Y
CA   Induced pluripotent stem cell
DT   Created: 05-03-18; Last updated: 29-10-20; Version: 5
RX   PubMed=26905200; DOI=10.1016/j.stemcr.2016.01.013;
RA   Fernandes H.J.R., Hartfield E.M., Christian H.C., Emmanoulidou E.,
RA   Zheng Y., Booth H., Bogetofte H., Lang C., Ryan B.J., Sardi S.P.,
RA   Badger J., Vowles J., Evetts S., Tofaris G.K., Vekrellis K.,
RA   Talbot K., Hu M.T., James W., Cowley S.A., Wade-Martins R.;
RT   "ER stress and autophagic perturbations lead to elevated extracellular
RT   alpha-synuclein in GBA-N370S Parkinson's iPSC-derived dopamine
RT   neurons.";
RL   Stem Cell Reports 6:342-356(2016).
RX   PubMed=28591653; DOI=10.1016/j.stemcr.2017.05.017;
RA   Haenseler W., Sansom S.N., Buchrieser J., Newey S.E., Moore C.S.,
RA   Nicholls F.J., Chintawar S., Schnell C., Antel J.P., Allen N.D.,
RA   Cader M.Z., Wade-Martins R., James W.S., Cowley S.A.;
RT   "A highly efficient human pluripotent stem cell microglia model
RT   displays a neuronal-co-culture-specific expression profile and
RT   inflammatory response.";
RL   Stem Cell Reports 8:1727-1742(2017).
RX   PubMed=28827786; DOI=10.1038/s41598-017-09362-3;
RA   Haenseler W., Zambon F., Lee H., Vowles J., Rinaldi F., Duggal G.,
RA   Houlden H., Gwinn K., Wray S., Luk K.C., Wade-Martins R., James W.S.,
RA   Cowley S.A.;
RT   "Excess alpha-synuclein compromises phagocytosis in iPSC-derived
RT   macrophages.";
RL   Sci. Rep. 7:9003-9003(2017).
RX   PubMed=32359446; DOI=10.1016/j.stemcr.2020.04.001;
RA   Lee H., Flynn R., Sharma I., Haberman E., Carling P.J., Nicholls F.J.,
RA   Stegmann M., Vowles J., Haenseler W., Wade-Martins R., James W.S.,
RA   Cowley S.A.;
RT   "LRRK2 is recruited to phagosomes and co-recruits RAB8 and RAB10 in
RT   human pluripotent stem cell-derived macrophages.";
RL   Stem Cell Reports 14:940-955(2020).