ID   Hepa/8F5
AC   CVCL_RI52
SY   Hepa/8F(#5); Hepa8F5
DR   ArrayExpress; E-MTAB-5770
DR   RCB; RCB4661
DR   Wikidata; Q54882819
RX   DOI=10.1016/j.bej.2011.10.004;
RX   PubMed=28847578;
RX   PubMed=34149171;
CC   Characteristics: When doxycycline-induced overexpresses 8 liver-enriched transcription factors (LETFs).
CC   Transfected with: MGI; MGI:99480; Cebpa.
CC   Transfected with: MGI; MGI:88373; Cebpb.
CC   Transfected with: MGI; MGI:104982; Cebpg.
CC   Transfected with: MGI; MGI:1347476; Foxa2.
CC   Transfected with: MGI; MGI:98504; Hnf1a.
CC   Transfected with: MGI; MGI:98505; Hnf1b.
CC   Transfected with: MGI; MGI:109128; Hnf4a.
CC   Transfected with: MGI; MGI:1196423; Onecut1.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Breed/subspecies: C57L.
DI   NCIt; C38756; Hepatocellular carcinoma of the mouse
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0327 ! Hepa 1-6
SX   Female
CA   Cancer cell line
DT   Created: 05-03-18; Last updated: 29-06-23; Version: 8
//
RX   DOI=10.1016/j.bej.2011.10.004;
RA   Yamamoto H., Kawabe Y., Ito A., Kamihira M.;
RT   "Enhanced liver functions in mouse hepatoma cells by induced
RT   overexpression of liver-enriched transcription factors.";
RL   Biochem. Eng. J. 60:67-73(2012).
//
RX   PubMed=28847578; DOI=10.1016/j.jbiosc.2017.07.011;
RA   Yamamoto H., Tonello J.M., Sambuichi T., Kawabe Y., Ito A.,
RA   Kamihira M.;
RT   "Characterization of genetically engineered mouse hepatoma cells with
RT   inducible liver functions by overexpression of liver-enriched
RT   transcription factors.";
RL   J. Biosci. Bioeng. 125:131-139(2018).
//
RX   PubMed=34149171; DOI=10.1007/s10616-021-00457-4;
RA   Kitano H., Nagae Y., Kawabe Y., Ito A., Kamihira M.;
RT   "Development of a genetically modified hepatoma cell line with
RT   heat-inducible high liver function.";
RL   Cytotechnology 73:353-362(2021).
//