ID   U2OS His10-SUMO-2-K0-Q87R
AC   CVCL_RJ63
DR   PRIDE; PXD004927
DR   PRIDE; PXD005296
DR   Wikidata; Q54973666
RX   PubMed=25755297;
RX   PubMed=28112733;
CC   Characteristics: Transfected with a decahistidine (His10) tagged lysine-deficient (K0) and Q87R SUMO2 and GFP separated by an internal ribosome entry site (IRES).
CC   Transfected with: HGNC; 11125; SUMO2 (with p.Lys11Arg, p.Lys32Arg, p.Lys32Arg, p.Lys34Arg, p.Lys41Arg, p.Lys44Arg and p.Gln87Arg).
CC   Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
CC   Omics: Sumoylated proteins analysis by proteomics.
CC   Derived from sampling site: Bone; tibia.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0042 ! U2OS
SX   Female
AG   15Y
CA   Cancer cell line
DT   Created: 05-03-18; Last updated: 12-03-20; Version: 3
//
RX   PubMed=25755297; DOI=10.1074/mcp.O114.044792;
RA   Xiao Z., Chang J.-G., Hendriks I.A., Sigurethsson J.O., Olsen J.V.,
RA   Vertegaal A.C.O.;
RT   "System-wide analysis of sumoylation dynamics in response to
RT   replication stress reveals novel small ubiquitin-like modified target
RT   proteins and acceptor lysines relevant for genome stability.";
RL   Mol. Cell. Proteomics 14:1419-1434(2015).
//
RX   PubMed=28112733; DOI=10.1038/nsmb.3366;
RA   Hendriks I.A., Lyon D., Young C., Jensen L.J., Vertegaal A.C.O.,
RA   Nielsen M.L.;
RT   "Site-specific mapping of the human SUMO proteome reveals
RT   co-modification with phosphorylation.";
RL   Nat. Struct. Mol. Biol. 24:325-336(2017).
//