Cellosaurus logo
expasy logo

Cellosaurus FT33-shp53-R24C (CVCL_RK66)

[Text version]
Cell line name FT33-shp53-R24C
Synonyms FT33; iFTSEC33
Accession CVCL_RK66
Resource Identification Initiative To cite this cell line use: FT33-shp53-R24C (RRID:CVCL_RK66)
Comments Knockout cell: Method=shRNA knockdown; HGNC; 11998; TP53.
Transfected with: HGNC; 1773; CDK4 (with p.Arg24Cys).
Transfected with: HGNC; 11730; TERT.
Omics: H3K27ac ChIP-seq epigenome analysis.
Omics: H3K4me1 ChIP-seq epigenome analysis.
Derived from site: In situ; Fallopian tube; UBERON=UBERON_0003889.
Cell type: Fallopian tube secretory epithelial cell; CL=CL_4030006.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Telomerase immortalized cell line
Publications

PubMed=21502498; DOI=10.1073/pnas.1017300108
Karst A.M., Levanon K., Drapkin R.I.
Modeling high-grade serous ovarian carcinogenesis from the fallopian tube.
Proc. Natl. Acad. Sci. U.S.A. 108:7547-7552(2011)

PubMed=22936217; DOI=10.1038/nprot.2012.097
Karst A.M., Drapkin R.I.
Primary culture and immortalization of human fallopian tube secretory epithelial cells.
Nat. Protoc. 7:1755-1764(2012)

PubMed=25804953; DOI=10.1093/hmg/ddv101
Coetzee S.G., Shen H.C., Hazelett D.J., Lawrenson K., Kuchenbaecker K., Tyrer J.P., Rhie S.K., Levanon K., Karst A.M., Drapkin R.I., Ramus S.J., Couch F.J., Offit K., Chenevix-Trench G., Monteiro A.N.A., Antoniou A., Freedman M.L., Coetzee G.A., Pharoah P.D.P., Noushmehr H., Gayther S.A.
Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci.
Hum. Mol. Genet. 24:3595-3607(2015)

PubMed=30487138; DOI=10.1158/0008-5472.CAN-17-3864
Buckley M.A., Woods N.T., Tyrer J.P., Mendoza-Fandino G., Lawrenson K., Hazelett D.J., Najafabadi H.S., Gjyshi A., Carvalho R.S., Lyra P.C. Jr., Coetzee S.G., Shen H.C., Yang A.W., Earp M.A., Yoder S.J., Risch H., Chenevix-Trench G., Ramus S.J., Phelan C.M., Coetzee G.A., Noushmehr H., Hughes T.R., Sellers T.A., Goode E.L., Pharoah P.D.P., Gayther S.A., Monteiro A.N.A.
Functional analysis and fine mapping of the 9p22.2 ovarian cancer susceptibility locus.
Cancer Res. 79:467-481(2019)

Cross-references
Cell line collections (Providers) ABM; T0609 - Discontinued
Encyclopedic resources Wikidata; Q54835216
Gene expression databases GEO; GSM1663024
GEO; GSM1663025
GEO; GSM1663026
GEO; GSM1663027
GEO; GSM1663028
GEO; GSM1663029
GEO; GSM1663030
GEO; GSM1663031
Entry history
Entry creation05-Mar-2018
Last entry update29-Jun-2023
Version number9