Cellosaurus HaCaT-TRS4 (CVCL_RL61)

Cell line name HaCaT-TRS4
Accession CVCL_RL61
Resource Identification Initiative To cite this cell line use: HaCaT-TRS4 (RRID:CVCL_RL61)
Comments Characteristics: Expresses tetracyclin-inducible SMAD4 siRNA.
Knockout cell: Method=siRNA knockdown; HGNC; 6770; SMAD4.
Transfected with: UniProtKB; P04483; E.coli Tn10 tetR.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0038 (HaCaT)
Sex of cell Male
Age at sampling 62Y
Category Spontaneously immortalized cell line
Publications

PubMed=16135802; DOI=10.1128/MCB.25.18.8108-8125.2005
Levy L., Hill C.S.
Smad4 dependency defines two classes of transforming growth factor beta (TGF-beta) target genes and distinguishes TGF-beta-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses.
Mol. Cell. Biol. 25:8108-8125(2005)