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Cellosaurus ME-2 (CVCL_RL95)

[Text version]

Cell line name ME-2
Accession CVCL_RL95
Resource Identification Initiative To cite this cell line use: ME-2 (RRID:CVCL_RL95)
Comments Population: Japanese.
Doubling time: 2-3 days (PubMed=8018932).
Derived from sampling site: Peripheral blood.
Sequence variations Gene fusion; HGNC; 1539; CBFB + HGNC; 7569; MYH11; Name(s)=CBFB-MYH11 (from parent cell line).
Mutation; HGNC; 7989; NRAS; Simple; p.Gln61His (c.183A>C); ClinVar=VCV000375871; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2110 (ME-1 [Human leukemia])
Children:
CVCL_G313 (ME-F2)
Sex of cell Male
Age at sampling 40Y
Category Cancer cell line
Publications

PubMed=8018932; DOI=10.1182/blood.V84.1.84.84
Yanagisawa K., Sato M., Horiuchi T., Hasegawa H., Fujita S.
Difference in response to colony-stimulating factors and involvement of protein kinase C signal transduction system in three subclones from the ME-1 cell line and two sublines.
Blood 84:84-93(1994)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

Cross-references
Other Wikidata; Q54904902
Entry history
Entry creation05-Mar-2018
Last entry update20-May-2021
Version number7