Cell line name |
A375P-5 |
Accession |
CVCL_RN37 |
Resource Identification Initiative |
To cite this cell line use: A375P-5 (RRID:CVCL_RN37) |
Comments |
Population: Caucasian. Derived from site: In situ; Skin; UBERON=UBERON_0002097. |
Sequence variations |
- Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 1787; CDKN2A; Simple; p.Glu61Ter (c.181G>T) (p.Gly75Val, c.224G>T); ClinVar=VCV000376309; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 1787; CDKN2A; Simple; p.Glu69Ter (c.205G>T) (p.Gly83Val, c.248G>T); ClinVar=VCV000376308; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
|
Disease |
Amelanotic melanoma (NCIt: C3802) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_6233 (A375-P) |
Sex of cell |
Female |
Age at sampling |
54Y |
Category |
Cancer cell line |
Publications | PubMed=2731157; DOI=10.1016/0304-3835(89)90148-1 Yohem K.H., Seftor E.A., Meyskens F.L. Jr., Hendrix M.J.C. Cloning efficiency of human melanoma cells is modulated after invasion through a reconstituted basement membrane. Cancer Lett. 45:135-143(1989) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_RN37
|
Encyclopedic resources |
Wikidata; Q54606871
|
Entry history |
Entry creation | 05-Mar-2018 |
Last entry update | 05-Oct-2023 |
Version number | 12 |
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