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Cellosaurus DLD-1 PIK3CA E545K KO (CVCL_RQ05)

[Text version]

Cell line name DLD-1 PIK3CA E545K KO
Synonyms PIK3CA^(+/-) DLD-1
Accession CVCL_RQ05
Resource Identification Initiative To cite this cell line use: DLD-1 PIK3CA E545K KO (RRID:CVCL_RQ05)
Comments Characteristics: Knockout of PIK3CA mutant allele (E545K) in heterozygous parental cells.
Knockout cell: Method=Recombinant Adeno-Associated Virus; HGNC; 8975; PIK3CA (with p.Glu545Lys).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0248 (DLD-1)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Web pages https://www.horizondiscovery.com/human-pik3ca-dld-1-cell-line-hd-105-001
Publications

PubMed=15950905; DOI=10.1016/j.ccr.2005.05.014
Samuels Y., Diaz L.A. Jr., Schmidt-Kittler O., Cummins J.M., Delong L., Cheong I., Rago C., Huso D.L., Lengauer C., Kinzler K.W., Vogelstein B., Velculescu V.E.
Mutant PIK3CA promotes cell growth and invasion of human cancer cells.
Cancer Cell 7:561-573(2005)

Cross-references
Other Wikidata; Q54831164
Entry history
Entry creation05-Mar-2018
Last entry updated07-Sep-2018
Version number2