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Cellosaurus IGR-39rPLX4720_20muM (CVCL_RR34)

[Text version]
Cell line name IGR-39rPLX4720_20muM
Synonyms IGR-39rPLX4720(20muM)
Accession CVCL_RR34
Resource Identification Initiative To cite this cell line use: IGR-39rPLX4720_20muM (RRID:CVCL_RR34)
Comments Part of: Resistant Cancer Cell Line (RCCL) collection.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:90295; PLX-4720 (PLX4720).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Cys229Tyrfs*10 (c.686_687delGT); ClinVar=VCV000863486; Zygosity=Unspecified (from parent cell line).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2076 (IGR-39)
Sex of cell Male
Age at sampling 26Y
Category Cancer cell line
Web pages https://www.wass-michaelislab.org/rccl.php
Cross-references
Cell line databases/resources cancercelllines; CVCL_RR34
Encyclopedic resources Wikidata; Q54897371
Entry history
Entry creation05-Mar-2018
Last entry update05-Oct-2023
Version number12